Marimastat from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemMarimastat
CompanyTocris Bioscience, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number2631/1
Quantity1 mg (also 10 mg)
Brand/TrademarkTocris, a Bio-Techne Brand
Purity0.99
Molecular Weight331.41
Molecule Name(2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide
FormulaC₁₅H₂₉N₃O₅
StorageStore at -20°C

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Cell fate coordinates mechano-osmotic forces in intestinal crypt formationNature cell biologyJuly 1, 2021Yang Q, Xue SL, Chan CJ, Rempfler M, Vischi D, Maurer-Gutierrez F, Hiiragi T, Hannezo E, Liberali P.GM6001(MMP inhibitor, R&D Systems cat# 2983/10), or 0.3 μM Marimastat (MMP inhibitor, R&D Systems cat# 2631/1) or 5 μM DMSO in ENR medium, from 72 hours until fixation at 96 hours. Organoid immunostaining and

(2) Bimodal fluorogenic sensing of matrix proteolytic signatures in lung cancerOrganic & biomolecular chemistryNovember 7, 2018Megia-Fernandez A, Mills B, Michels C, Chankeshwara SV, Krstajić N, Haslett C, Dhaliwal K, Bradley M.

(3) Matrix mechanical plasticity regulates cancer cell migration through confining microenvironmentsNature communicationsOctober 8, 2018Wisdom KM, Adebowale K, Chang J, Lee JY, Nam S, Desai R, Rossen NS, Rafat M, West RB, Hodgson L, et al.

(4) Evaluating the potential of endothelial cells derived from human induced pluripotent stem cells to form microvascular networks in 3D culturesScientific reportsFebruary 8, 2018Bezenah JR, Kong YP, Putnam AJ.

(5) Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomersMolecular biology of the cellOctober 1, 2017Pitt J, Wilcox KC, Tortelli V, Diniz LP, Oliveira MS, Dobbins C, Yu XW, Nandamuri S, Gomes FCA, DiNunno N, et al.

(6) Human stem cells alter the invasive properties of somatic cells via paracrine activation of mTORC1Nature communicationsSeptember 19, 2017Rosner M, Pham HTT, Moriggl R, Hengstschläger M.

(7) Matrix degradability controls multicellularity of 3D cell migrationNature communicationsAugust 29, 2017Trappmann B, Baker BM, Polacheck WJ, Choi CK, Burdick JA, Chen CS.

(8) Adam17 Deficiency Promotes Atherosclerosis by Enhanced TNFR2 Signaling in MiceArteriosclerosis, thrombosis, and vascular biologyFebruary 1, 2017Nicolaou A, Zhao Z, Northoff BH, Sass K, Herbst A, Kohlmaier A, Chalaris A, Wolfrum C, Weber C, Steffens S, et al.

(9) Signaling pathways induced by serine proteases to increase intestinal epithelial barrier functionPloS oneJanuary 1, 2017Lahey KA, Ronaghan NJ, Shang J, Dion SP, Désilets A, Leduc R, MacNaughton WK.

(10) Discovery of an enzyme and substrate selective inhibitor of ADAM10 using an exosite-binding glycosylated substrateScientific reportsDecember 5, 2016Madoux F, Dreymuller D, Pettiloud JP, Santos R, Becker-Pauly C, Ludwig A, Fields GB, Bannister T, Spicer TP, Cudic M, et al.

(11) WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-γ pathwaysBritish journal of cancerSeptember 15, 2015Ji J, Jia S, Jia Y, Ji K, Hargest R, Jiang WG.

(12) SAR Studies of Exosite-Binding Substrate-Selective Inhibitors of A Disintegrin And Metalloprotease 17 (ADAM17) and Application as Selective in Vitro ProbesJournal of medicinal chemistryAugust 13, 2015Knapinska AM, Dreymuller D, Ludwig A, Smith L, Golubkov V, Sohail A, Fridman R, Giulianotti M, LaVoi TM, Houghten RA, et al.

(13) Cleavage/alteration of interleukin-8 by matrix metalloproteinase-9 in the female lower genital tractPloS oneJanuary 1, 2015Zariffard MR, Anastos K, French AL, Munyazesa E, Cohen M, Landay AL, Spear GT.

(14) Nestin depletion induces melanoma matrix metalloproteinases and invasionLaboratory investigation; a journal of technical methods and pathologyDecember 1, 2014Lee CW, Zhan Q, Lezcano C, Frank MH, Huang J, Larson AR, Lin JY, Wan MT, Lin PI, Ma J, et al.

(15) NME1 suppression promotes growth, adhesion and implantation of endometrial stromal cells via Akt and MAPK/Erk1/2 signal pathways in the endometriotic milieuHuman reproduction (Oxford, England)October 1, 2013Li MQ, Shao J, Meng YH, Mei J, Wang Y, Li H, Zhang L, Chang KK, Wang XQ, Zhu XY, et al.

(16) Inhibition of ADAM-17 more effectively down-regulates the Notch pathway than that of γ-secretase in renal carcinomaJournal of experimental & clinical cancer research : CRMay 9, 2013Guo Z, Jin X, Jia H.

(17) Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactionsCell death and differentiationMarch 1, 2013Brafman DA, Phung C, Kumar N, Willert K.

(18) Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activationThe Journal of biological chemistryDecember 7, 2012Yurtsever Z, Sala-Rabanal M, Randolph DT, Scheaffer SM, Roswit WT, Alevy YG, Patel AC, Heier RF, Romero AG, Nichols CG, et al.

(19) Bone marrow stromal cells stimulate an angiogenic program that requires endothelial MT1-MMPJournal of cellular physiologyNovember 1, 2012Kachgal S, Carrion B, Janson IA, Putnam AJ.

(20) The metalloproteinase inhibitor Reck is essential for zebrafish DRG developmentDevelopment (Cambridge, England)March 1, 2012Prendergast A, Linbo TH, Swarts T, Ungos JM, McGraw HF, Krispin S, Weinstein BM, Raible DW.

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Marimastat

Marimastat from Tocris Bioscience, a Bio-Techne Brand

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Tocris Bioscience, a Bio-Techne Brand

Citations (23)

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Marimastat from Tocris Bioscience, a Bio-Techne Brand

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